Use of Low Copy Number (lcn) Dna in Forensic Inference
نویسندگان
چکیده
Development of a low copy number DNA profiling method has allowed the detection of very low levels of DNA. However, issues concerning the transfer and persistence of LCN DNA have required further research to be carried out; this has included studies of individuals’ tendency to deposit and transfer DNA onto surfaces they have touched. Additionally, the effect on DNA of some of the enhancement treatments used on latent finger marks has been tested.
منابع مشابه
Direct comparison of post-28-cycle PCR purification and modified capillary electrophoresis methods with the 34-cycle "low copy number" (LCN) method for analysis of trace forensic DNA samples.
The investigation of samples with low amounts of template DNA remains at the forefront of forensic DNA research and technology as it becomes increasingly important to gain DNA profile information from exceedingly trace levels of DNA. Previous studies have demonstrated that it is possible to obtain short tandem repeat (STR) profiles from <100pg of template DNA by increasing the number of amplifi...
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